DPP4 antibody (AA 1-200)

Catalog No. ABIN7868465

This Mouse Monoclonal antibody specifically detects DPP4 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for DPP4 antibody (AA 1-200) (ABIN7868465)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DPP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: DPP4-7415

Product Details anti-DPP4 Antibody

Binding Specificity: AA 1-200

Purpose: CD26 Antibody / Dipeptidyl peptidase 4

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the CD26 antibody.

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal dilution of the CD26 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD26 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Alternative Name: CD26

Background: Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this mAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity