PLK1 antibody (AA 1-200)

Catalog No. ABIN7868708

This Mouse Monoclonal antibody specifically detects PLK1 in ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PLK1 antibody (AA 1-200) (ABIN7868708)

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLK1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: PLK1-7122

Product Details anti-PLK1 Antibody

Binding Specificity: AA 1-200

Purpose: Polo like kinase 1 Antibody / PLK1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human protein (within amino acids 1-200) was used as the immunogen for the Polo like kinase 1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Polo like kinase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Polo like kinase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PLK1

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Alternative Name: Polo like kinase 1

Background: Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle, Plk protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.

UniProt: P53350

Pathways: Cell Division Cycle, M Phase