CRTC3 antibody (AA 116-619)

Catalog No. ABIN7870242

The Rabbit Polyclonal anti-CRTC3 antibody is suitable to detect CRTC3 in samples from Human and Monkey. It has been validated for WB, ELISA, IF, IHC (p) and FACS.

Quick Overview for CRTC3 antibody (AA 116-619) (ABIN7870242)

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-CRTC3 Antibody

Binding Specificity: AA 116-619

Purpose: CRTC3 Antibody / TORC3

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids R116-L619) was used as the immunogen for the CRTC3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CRTC3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CRTC3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Alternative Name: CRTC3

Background: CREB-regulated transcription coactivator 3 is a protein that in humans is encoded by the CRTC3 gene. This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

UniProt: Q6UUV7

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection