ALDH5A1 antibody (AA 128-157)

Catalog No. ABIN7870410

The Rabbit Polyclonal anti-ALDH5A1 antibody is suitable to detect ALDH5A1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for ALDH5A1 antibody (AA 128-157) (ABIN7870410)

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH5A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ALDH5A1 Antibody

Binding Specificity: AA 128-157

Purpose: ALDH5A1 Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 128-157 from the human protein was used as the immunogen for the ALDH5A1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the ALDH5A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ALDH5A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ALDH5A1

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Alternative Name: ALDH5A1

Background: ALDH5A1 belongs to the aldehyde dehydrogenase family of proteins. This protein functions as a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties.

UniProt: P51649

Pathways: Monocarboxylic Acid Catabolic Process