NDFIP2 antibody (AA 16-336)

Catalog No. ABIN7871068

The Mouse Monoclonal anti-NDFIP2 antibody (Clone 10D6D7) (ABIN7871068) specifically detects NDFIP2 in WB, FACS, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for NDFIP2 antibody (AA 16-336) (ABIN7871068)

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NDFIP2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 10D6D7

Product Details anti-NDFIP2 Antibody

Binding Specificity: AA 16-336

Purpose: NDFIP2 Antibody / NEDD4 family-interacting protein 2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M16-L336) was used as the immunogen for the NDFIP2 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the NDFIP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NDFIP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NDFIP2

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Alternative Name: NDFIP2

Background: NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene. The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

UniProt: Q9NV92

Pathways: Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome