LNPEP antibody (AA 17-994)

Catalog No. ABIN7871245

The Rabbit Polyclonal anti-LNPEP antibody (ABIN7871245) specifically detects LNPEP in WB, ELISA and IHC (p). The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for LNPEP antibody (AA 17-994) (ABIN7871245)

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LNPEP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LNPEP Antibody

Binding Specificity: AA 17-994

Purpose: LNPEP Antibody / OTase

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E17-T994) was used as the immunogen for the LNPEP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the LNPEP antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the LNPEP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LNPEP

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Alternative Name: LNPEP

Background: Leucyl/cystinyl aminopeptidase, also known as cystinyl aminopeptidase (CAP), insulin-regulated aminopeptidase (IRAP), human placental leucine aminopeptidase (PLAP), oxytocinase, and vasopressinase, is an enzyme of the aminopeptidase group that in humans is encoded by the LNPEP gene. This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q9UIQ6

Pathways: Regulation of long-term Neuronal Synaptic Plasticity