Tec Protein Tyrosine Kinase (TEC) (AA 175-205) antibody

Catalog No. ABIN7871303

This Rabbit Polyclonal antibody specifically detects Tec Protein Tyrosine Kinase in WB, IF and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for Tec Protein Tyrosine Kinase (TEC) (AA 175-205) antibody (ABIN7871303)

Target: Tec Protein Tyrosine Kinase (TEC)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 175-205

Purpose: TEC Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 175-205 from the human protein was used as the immunogen for the TEC antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the TEC antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TEC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details

Target: Tec Protein Tyrosine Kinase (TEC)

Alternative Name: TEC

Background: TEC belongs to the TEC subfamily of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. TEC family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. TEC kinase is an integral component of T cell signaling and has a distinct role in T cell activation. TEC may be associated with myelodysplastic syndrome.

UniProt: P42680

Pathways: Fc-epsilon Receptor Signaling Pathway