IL-21 antibody (AA 18-146)

Catalog No. ABIN7871383

The Rabbit Polyclonal anti-IL-21 antibody (ABIN7871383) specifically detects IL-21 in ELISA and IHC (p). The antibody is reactive with Mouse and Rat samples.

Quick Overview for IL-21 antibody (AA 18-146) (ABIN7871383)

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-21 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IL-21 Antibody

Binding Specificity: AA 18-146

Purpose: Il-21 Antibody

Purification: Affinity purified

Immunogen: A mouse recombinant partial protein (amino acids H18-S146) was used as the immunogen for the Il-21 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Il-21 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Il-21 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for IL-21

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Alternative Name: Il-21

Background: Interleukin 21 (IL-21) is a protein that in humans is encoded by the IL21 gene. This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UniProt: Q9ES17

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response