IQGAP1 antibody (AA 2-578)

Catalog No. ABIN7871823

The Rabbit Polyclonal anti-IQGAP1 antibody is suitable to detect IQGAP1 in samples from Human. It has been validated for WB, ELISA, IF, FACS and IHC (p).

Quick Overview for IQGAP1 antibody (AA 2-578) (ABIN7871823)

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQGAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IQGAP1 Antibody

Binding Specificity: AA 2-578

Purpose: IQGAP1 Antibody

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids S2-H578) was used as the immunogen for the IQGAP1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IQGAP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the IQGAP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for IQGAP1

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Alternative Name: IQGAP1

Background: Ras GTPase-activating-like protein (IQGAP1) also known as p195 is a ubiquitously expressed protein that in humans is encoded by the IQGAP1 gene. It is mapped to 15q26.1. This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

UniProt: P46940

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2