JAG2 antibody (AA 22-1153)

Catalog No. ABIN7872266

This Rabbit Polyclonal antibody specifically detects JAG2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for JAG2 antibody (AA 22-1153) (ABIN7872266)

Target: JAG2 (Jagged 2 (JAG2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-JAG2 Antibody

Binding Specificity: AA 22-1153

Purpose: JAG2 Antibody / Jagged 2

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids Q22-N1153) was used as the immunogen for the JAG2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the JAG2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the JAG2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for JAG2

Target: JAG2 (Jagged 2 (JAG2))

Alternative Name: JAG2

Background: Protein jagged-2, also known as SER2, is a protein that in humans is encoded by the JAG2 gene. It is mapped to 14q32.33. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Notch ligands Delta1 and JAG2 are subject to presenilin-dependent, intramembranous gamma-secretase processing, resulting in the production of soluble intracellular derivatives. JAG2 can promote the growth and dissemination of uveal melanoma cells.

UniProt: Q9Y219

Pathways: Notch Signaling, Sensory Perception of Sound