Poliovirus Receptor antibody (AA 24-345)

Catalog No. ABIN7872685

The Rabbit Polyclonal anti-Poliovirus Receptor antibody (ABIN7872685) specifically detects Poliovirus Receptor in WB and ELISA. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Poliovirus Receptor antibody (AA 24-345) (ABIN7872685)

Target: Poliovirus Receptor (PVR)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Poliovirus Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Poliovirus Receptor Antibody

Binding Specificity: AA 24-345

Purpose: Pvr Antibody / Poliovirus receptor / Cd155

Purification: Antigen affinity purified

Immunogen: Recombinant mouse protein (amino acids R24-R345) was used as the immunogen for the Pvr antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Pvr antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Pvr antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Alternative Name: Pvr

Background: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q91WP1

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome