Choline Acetyltransferase antibody (AA 25-731)

Catalog No. ABIN7872891

The Rabbit Polyclonal anti-Choline Acetyltransferase antibody is suitable to detect Choline Acetyltransferase in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF, FACS and IHC (p).

Quick Overview for Choline Acetyltransferase antibody (AA 25-731) (ABIN7872891)

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Choline Acetyltransferase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Choline Acetyltransferase Antibody

Binding Specificity: AA 25-731

Purpose: ChAT Antibody / Choline Acetyltransferase

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids T25-K731) was used as the immunogen for the ChAT antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ChAT antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ChAT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Choline Acetyltransferase

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Alternative Name: ChAT

Background: Choline acetyltransferase (commonly abbreviated as ChAT or CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. In humans, the choline acetyltransferase enzyme is encoded by the CHAT gene. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.

UniProt: P28329

Pathways: Skeletal Muscle Fiber Development