MAP2K4 antibody (AA 259-287)

Catalog No. ABIN7872976

The Rabbit Polyclonal anti-MAP2K4 antibody (ABIN7872976) specifically detects MAP2K4 in WB and IHC (p). The antibody is reactive with Human, Mouse and Zebrafish (Danio rerio) samples.

Quick Overview for MAP2K4 antibody (AA 259-287) (ABIN7872976)

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Reactivity: Human, Mouse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MAP2K4 Antibody

Binding Specificity: AA 259-287

Purpose: MEK4 Antibody / MKK4 / MAP2K4

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 259-287 from the mouse protein was used as the immunogen for the MEK4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the MEK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the MEK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MAP2K4

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Alternative Name: MEK4

Background: Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).

UniProt: P47809

Pathways: MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling