MYBL2 antibody (AA 31-695)

Catalog No. ABIN7873801

The Rabbit Polyclonal anti-MYBL2 antibody (ABIN7873801) specifically detects MYBL2 in WB, ELISA, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for MYBL2 antibody (AA 31-695) (ABIN7873801)

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYBL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-MYBL2 Antibody

Binding Specificity: AA 31-695

Purpose: B-Myb Antibody / Myb-related protein B / MYBL2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K31-R695) was used as the immunogen for the B-Myb antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the B-Myb antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the B-Myb antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MYBL2

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Alternative Name: B-Myb

Background: Myb-related protein B is a protein that in humans is encoded by the MYBL2 gene. The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. Barletta et al.(1991) assigned the MYBL2 gene to chromosome Xq13. However, Noben-Trauth et al.(1996) demonstrated that this assignment was an error. Using mouse Mybl2 cDNA clones as probes, they assigned Mybl2 in an interspecific backcross panel to distal mouse chromosome 2. Using human cDNA probes in combination with fluorescence in situ hybridization analysis, they localized MYBL2 to chromosome 20q13.1, a region that is commonly deleted in myeloid disorders and shows high homology of synteny to mouse chromosome 2. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.

UniProt: P10244

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding