MCU antibody (AA 51-351)

Catalog No. ABIN7875517

The Rabbit Polyclonal anti-MCU antibody (ABIN7875517) specifically detects MCU in ELISA, WB, FACS and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MCU antibody (AA 51-351) (ABIN7875517)

Target: MCU (Mitochondrial Calcium Uniporter (MCU))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCU antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MCU Antibody

Binding Specificity: AA 51-351

Purpose: MCU Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids V51-D351) was used as the immunogen for the MCU antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MCU antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MCU antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MCU

Target: MCU (Mitochondrial Calcium Uniporter (MCU))

Alternative Name: MCU

Background: The mitochondrial calcium uniporter (MCU) is a transmembrane protein that allows the passage of calcium ions from a cell's cytosol into mitochondria. Its activity is regulated by MICU1 and MICU2, which together with the MCU make up the mitochondrial calcium uniporter complex. This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants.

UniProt: Q8NE86

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis