DUOX2 antibody (AA 63-403)

Catalog No. ABIN7876239

The Rabbit Polyclonal anti-DUOX2 antibody is suitable to detect DUOX2 in samples from Rat and Mouse. It has been validated for WB, ELISA and IHC (p).

Quick Overview for DUOX2 antibody (AA 63-403) (ABIN7876239)

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUOX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DUOX2 Antibody

Binding Specificity: AA 63-403

Purpose: Duox2 Antibody

Purification: Affinity purified

Immunogen: An E. coli-derived mouse protein (amino acids A63-D403) was used as the immunogen for the Duox2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Duox2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Duox2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DUOX2

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Alternative Name: Duox2

Background: Dual oxidase 2, also known as DUOX2 or ThOX2 (for thyroid oxidase), is an enzyme that in humans is encoded by the DUOX2 gene. The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.

UniProt: B7ZWM4

Pathways: Thyroid Hormone Synthesis