DCLK1 antibody (AA 690-720)

Catalog No. ABIN7876455

The Rabbit Polyclonal anti-DCLK1 antibody is suitable to detect DCLK1 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for DCLK1 antibody (AA 690-720) (ABIN7876455)

Target: DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCLK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DCLK1 Antibody

Binding Specificity: AA 690-720

Purpose: DCAMKL1 Antibody / Doublecortin-like and CAM kinase-like 1 / DCLK1

Purification: Antigen affinity

Immunogen: A portion of amino acids 690-720 from the human protein was used as the immunogen for this DCAMKL1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the DCAMKL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the DCAMKL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DCLK1

Target: DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

Alternative Name: DCAMKL1

Background: This gene encodes a member of the protein kinase superfamily and the doublecortin family called Doublecortin-like and CAM kinase-like 1 (DCAMKL1) or Doublecortin-like kinase 1 (DCLK1). The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity.

UniProt: Q9JLM8