GZMB antibody (AA 73-187) (Biotin)

Catalog No. ABIN7876659

The Mouse Monoclonal anti-GZMB antibody is suitable to detect GZMB in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for GZMB antibody (AA 73-187) (Biotin) (ABIN7876659)

Target: GZMB (Granzyme B (GZMB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GZMB antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GZMB-3014

Product Details anti-GZMB Antibody (Biotin)

Binding Specificity: AA 73-187

Purpose: Granzyme B Antibody

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 73-187 from the human protein was used as the immunogen for the Granzyme B antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Granzyme B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Granzyme B antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).

Target Details for GZMB

Target: GZMB (Granzyme B (GZMB))

Alternative Name: Granzyme B

Background: Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface s Disease.

UniProt: P10144

Pathways: Apoptosis, Caspase Cascade in Apoptosis