NGFB antibody (AA 84-115)

Catalog No. ABIN7876952

This Rabbit Polyclonal antibody specifically detects NGFB in WB, IHC (p), FACS and IF. It exhibits reactivity toward Human.

Quick Overview for NGFB antibody (AA 84-115) (ABIN7876952)

Target: NGFB (Nerve Growth Factor beta (NGFB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NGFB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-NGFB Antibody

Binding Specificity: AA 84-115

Purpose: Beta-nerve growth factor Antibody / NGF

Purification: Purified

Immunogen: A portion of amino acids 84-115 from the human protein was used as the immunogen for the Beta-nerve growth factor antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Beta-nerve growth factor antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Beta-nerve growth factor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NGFB

Target: NGFB (Nerve Growth Factor beta (NGFB))

Alternative Name: Beta-nerve growth factor

Background: NGFB is a member of the NGF-beta family. It is a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in the gene encoding NGFB have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of the gene's expression is associated with allergic rhinitis.

UniProt: P01138

Pathways: NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size