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PLK1 antibody (AA 86-430)

Name: PLK1 antibody (AA 86-430)
SKU: ABIN7876998
Availability: InStock

The Mouse Monoclonal anti-PLK1 antibody is suitable to detect PLK1 in samples from Human, Mouse, Rat and Monkey. It has been validated for WB and IHC (p).

Catalog No. ABIN7876998

$625.62

Plus shipping costs $50.00

100 μg

Shipping to: United States

Delivery in 2 to 4 Business Days

Quick Overview for PLK1 antibody (AA 86-430) (ABIN7876998)

Target

See all PLK1 Antibodies

PLK1 (Polo-Like Kinase 1 (PLK1))

Reactivity

Human, Mouse, Rat, Monkey

Host

Mouse

Clonality

Monoclonal

Conjugate

This PLK1 antibody is un-conjugated

Application

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

6D11

Discover our top product PLK1 Primary Antibody

Binding Specificity
31

25

23

15

12

8

5

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 86-430

Purpose

PLK1 Antibody

Purification

Affinity purified

Immunogen

A human recombinant protein (amino acids K86-N430) was used as the immunogen for the PLK1 antibody.

Isotype

IgG2b
anti-Polo-Like Kinase 1 (PLK1) (AA 331-508) antibody
PLK1 Reactivity: Human, Mouse WB, ELISA, IHC, FACS Host: Mouse Monoclonal 3C11 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 1-603) antibody
PLK1 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 4G11 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 1-603) antibody
PLK1 Reactivity: Human WB, ELISA, IF, IP, PLA Host: Mouse Monoclonal 2G12 unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 Reactivity: Human, Dog WB, IHC, IP, IHC (p) Host: Mouse Monoclonal 6C6 unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 Reactivity: Human WB, IHC, IP, IHC (p), FACS Host: Mouse Monoclonal 5C1 unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 Reactivity: Human WB, IHC, IP, IHC (p) Host: Mouse Monoclonal 1D4 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 304-603) antibody
PLK1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 Reactivity: Human, Monkey, Dog WB, IF, IP, FACS Host: Mouse Monoclonal 8C12 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 331-508) antibody
PLK1 Reactivity: Human ELISA, ICC Host: Mouse Monoclonal 1D1 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 201-300) antibody
PLK1 Reactivity: Human WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal dilution of the PLK1 antibody should be determined by the researcher.

Restrictions

For Research Use only
Format

Lyophilized

Buffer

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage

4 °C,-20 °C

Storage Comment

After reconstitution, the PLK1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target

PLK1 (Polo-Like Kinase 1 (PLK1))

Alternative Name

PLK1

Background

Serine/threonine-protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13 (STPK13), is an enzyme that in humans is encoded by the PLK1 (polo-like kinase1) gene. Plk1 is an early trigger for G2/M transition. It supports the functional maturation of the centrosome in late G2/early prophase and establishment of the bipolar spindle. Also, Plk1 phosphorylates and activates cdc25C, a phosphatase that dephosphorylates and activates the cyclinB/cdc2 complex. Studies have shown that the loss of PLK1 expression can induce pro-apoptotic pathways and inhibit growth. Based on yeast and murine studies of meiosis, human PLK1 may also have a regulatory function in meiosis.

UniProt

P53350

Pathways

Cell Division Cycle, M Phase