Recombinant CD47 antibody (full length)

Catalog No. ABIN7877919

The Mouse Monoclonal anti-CD47 antibody is suitable to detect CD47 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant CD47 antibody (full length) (ABIN7877919)

Target: CD47

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD47 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RCD47-6365

Product Details anti-CD47 Antibody

Binding Specificity: full length

Purpose: Recombinant Integrin Associated Protein Antibody / IAP / CD47

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the recombinant Integrin Associated Protein antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Integrin Associated Protein antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant Integrin Associated Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD47

Target: CD47

Alternative Name: Integrin Associated Protein

Background: This antibody reacts with Ig domain of CD47/Integrin Associated Protein/IAP protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. It plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47/IAP may play a role in membrane transport and/or integrin dependent signal transduction.

UniProt: Q08722