Keratin 5/6 antibody (full length)

Catalog No. ABIN7878498

The Mouse Monoclonal anti-Keratin 5/6 antibody is suitable to detect Keratin 5/6 in samples from Human. It has been validated for IHC (p).

Quick Overview for Keratin 5/6 antibody (full length) (ABIN7878498)

Target: Keratin 5/6 (KRT5/6)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Keratin 5/6 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: KRT5-6-4866

Product Details anti-Keratin 5/6 Antibody

Binding Specificity: full length

Purpose: Cytokeratin 5/6 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length human KRT5 protein was used as the immunogen for the Cytokeratin 5/6 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Cytokeratin 5/6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Cytokeratin 5/6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Keratin 5/6

Target: Keratin 5/6 (KRT5/6)

Alternative Name: Cytokeratin 5/6

Background: It recognizes polypeptides of 58 kDa and 56 kDa, identified as cytokeratin 5 and 6 respectively. It shows no reaction with keratin 1, 8, or 19. It stains the basal cells of squamous and glandular epithelia, part of stratum spinosum of squamous epithelium, myoepithelium, and mesothelium. It does not stain adenous epithelium. Therefore, this antibody can be used to distinguish squamous carcinoma from adenocarcinoma, and to differentiate epitheliod mesothelioma from non-epitheliod mesothelioma and adenocarcinoma. It is also a useful antibody in the identification of mesothelioma and lung squamous cell carcinoma. It does not react with pulmonary adenocarcinoma.

UniProt: P13647