Angiotensin I Converting Enzyme 1 antibody

Catalog No. ABIN7879972

The Rabbit Monoclonal anti-Angiotensin I Converting Enzyme 1 antibody (Clone ADCO-1) (ABIN7879972) specifically detects Angiotensin I Converting Enzyme 1 in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for Angiotensin I Converting Enzyme 1 antibody (ABIN7879972)

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Angiotensin I Converting Enzyme 1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: ADCO-1

Product Details anti-Angiotensin I Converting Enzyme 1 Antibody

Purpose: ACE Antibody / Angiotensin-Converting Enzyme

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Angiotensin-Converting Enzyme was used as the immunogen for the ACE antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ACE antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the ACE antibody at -20oC.

Target Details for Angiotensin I Converting Enzyme 1

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Alternative Name: ACE

Background: The ACE gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [RefSeq]

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration