AIF antibody

Catalog No. ABIN7879991

This Rabbit Monoclonal antibody specifically detects AIF in WB. It exhibits reactivity toward Human.

Quick Overview for AIF antibody (ABIN7879991)

Target: AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This AIF antibody is un-conjugated

Application: Western Blotting (WB)

Clone: GH-1

Product Details anti-AIF Antibody

Purpose: AIFM1 Antibody / AIF / Apoptosis-Inducing Factor

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human AIF / AIFM1 was used as the immunogen for the AIFM1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the AIFM1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the AIFM1 antibody at -20oC.

Target Details for AIF

Target: AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

Alternative Name: AIFM1

Background: Apoptosis-inducing factor 1, mitochondrial' functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity.

UniProt: O95831

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect