CD46 antibody

Catalog No. ABIN7880328

The Rabbit Monoclonal anti-CD46 antibody is suitable to detect CD46 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for CD46 antibody (ABIN7880328)

Target: CD46

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD46 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AEI-3

Product Details anti-CD46 Antibody

Purpose: CD46 Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human CD46 was used as the immunogen for the CD46 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CD46 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the CD46 antibody at -20oC.

Target Details for CD46

Target: CD46

Alternative Name: CD46

Background: The protein encoded by the CD46 gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. [RefSeq]

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization