Recombinant CRTC2 antibody

Catalog No. ABIN7880510

This Rabbit Monoclonal antibody specifically detects CRTC2 in WB. It exhibits reactivity toward Human.

Quick Overview for Recombinant CRTC2 antibody (ABIN7880510)

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CRTC2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 28C77

Product Details anti-CRTC2 Antibody

Purpose: CRTC2 Antibody / TORC2

Purification: Affinity chromatography

Immunogen: A synthetic peptide from human CREB-regulated transcription coactivator 2 protein was used as the immunogen for the CRTC2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CRTC2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the CRTC2 antibody at -20oC.

Target Details for CRTC2

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Alternative Name: CRTC2

Background: CRTC2 is a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. [UniProt]

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis