IFNA1 antibody

Catalog No. ABIN7881253

The Mouse Monoclonal anti-IFNA1 antibody (Clone 2-48) (ABIN7881253) specifically detects IFNA1 in WB, FACS and IF. The antibody is reactive with Human samples.

Quick Overview for IFNA1 antibody (ABIN7881253)

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IFNA1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 2-48

Product Details anti-IFNA1 Antibody

Purpose: IFNA1 Antibody / Interferon alpha 1

Purification: Protein G affinity chromatography

Immunogen: Purified recombinant human protein was used as the immunogen for the Interferon alpha antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the IFNA1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the IFNA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Alternative Name: IFNA1

Background: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

UniProt: P01562

Pathways: JAK-STAT Signaling, Hepatitis C