Recombinant Keratin Acidic (AE1) antibody

Catalog No. ABIN7881424

The Mouse Monoclonal anti-Keratin Acidic antibody is suitable to detect Keratin Acidic in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant Keratin Acidic (AE1) antibody (ABIN7881424)

Target: Keratin Acidic (AE1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: RKRTL-6616

Product Details

Purpose: Recombinant Acidic Cytokeratin Antibody (LMW / Type I) (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A synthetic peptide sequence common to Type I Cytokeratins was used as the immunogen for the recombinant Acidic Cytokeratin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Acidic Cytokeratin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant Acidic Cytokeratin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details

Target: Keratin Acidic (AE1)

Alternative Name: Acidic Cytokeratin

Background: The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. Its usually used in a cytokeratin cocktail with type II cytokeratin antibody.

UniProt: Q7Z794