Recombinant Myosin VIIA antibody

Catalog No. ABIN7881738

This Rabbit Monoclonal antibody specifically detects Myosin VIIA in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant Myosin VIIA antibody (ABIN7881738)

Target: Myosin VIIA (MYO7A)

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Myosin VIIA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AFCH-13

Product Details anti-Myosin VIIA Antibody

Purpose: MYO7A Antibody / Unconventional Myosin-VIIa

Purification: Affinity chromatography

Immunogen: A peptide sequence specific to Unconventional Myosin-VIIa was used as the immunogen for the MYO7A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MYO7A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MYO7A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Myosin VIIA

Target: Myosin VIIA (MYO7A)

Alternative Name: MYO7A

Background: Unconventional Myosin-VIIa (MYO7A) is an actin-based motor protein involved in intracellular transport and structural organization within sensory cells. It plays a critical role in the function of hair cells in the inner ear and photoreceptor cells in the retina, contributing to mechanosensory and visual processes.

Mutations in MYO7A are associated with hereditary hearing loss, Usher syndrome type 1B, and certain forms of retinitis pigmentosa. MYO7A is essential for maintaining stereocilia structure in cochlear hair cells and for transporting opsin-containing vesicles in retinal cells, highlighting its importance in sensory cell maintenance and signaling.

Using a high-quality MYO7A antibody enables sensitive detection in applications such as western blot, immunohistochemistry, and immunofluorescence. An MYO7A antibody from NSJ Bioreagents provides consistent performance for research into sensory biology, genetic disorders, and intracellular transport mechanisms. Selecting the right MYO7A antibody is essential for achieving accurate and reproducible results.

UniProt: Q13402

Pathways: Sensory Perception of Sound