NGFB antibody

Catalog No. ABIN7881776

The Rabbit Polyclonal anti-NGFB antibody (ABIN7881776) specifically detects NGFB in WB. The antibody is reactive with Human samples.

Quick Overview for NGFB antibody (ABIN7881776)

Target: NGFB (Nerve Growth Factor beta (NGFB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NGFB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NGFB Antibody

Purpose: Beta NGF Antibody / NGF

Sequence: THTFVKALTM DGKQAAWRFI RID

Purification: Affinity purified

Immunogen: Amino acids THTFVKALTMDGKQAAWRFIRID from the human protein were used as the immunogen for the Beta NGF antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NGF antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Beta NGF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NGFB

Target: NGFB (Nerve Growth Factor beta (NGFB))

Alternative Name: Beta NGF

Background: Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. It is mapped to 1p13.2. This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.

UniProt: P01138

Pathways: NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size