Recombinant CHEK1 antibody

Catalog No. ABIN7938093

The Rabbit Monoclonal anti-CHEK1 antibody (Clone 2G7) (ABIN7938093) specifically detects CHEK1 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant CHEK1 antibody (ABIN7938093)

Target: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CHEK1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 2G7

Product Details anti-CHEK1 Antibody

Purpose: CHK1 antibody (rAb), 100 μg (Clone 2G7)

Purification: Protein A Chromatography

Immunogen: This information is proprietary to Active Motif and/or its suppliers.

Isotype: IgG

Application Details

Application Notes: WB: 1:5000-1:50000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for CHEK1

Target: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Alternative Name: CHK1

Background:

Background_Plain: CHK1 (CHEK1, Checkpoint kinase-1) belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell nuclear antigen and FANCD2 monoubiquitinylation. CHEK1 protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle function is disrupted.

Aliases: CHK1 checkpoint homolog

Molecular Weight: 54 kDa

Pathways: p53 Signaling, Apoptosis, Cell Division Cycle, DNA Damage Repair