CISD2 antibody (AA 55-124) (Biotin)

Catalog No. ABIN7977692

The Biotin-conjugated Rabbit Polyclonal anti-CISD2 antibody (ABIN7977692) specifically detects CISD2 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for CISD2 antibody (AA 55-124) (Biotin) (ABIN7977692)

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CISD2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CISD2 Antibody (Biotin)

Binding Specificity: AA 55-124

Purpose: Anti-CISD2 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CISD2 recombinant protein (Position: A55-N124).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CISD2

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Alternative Name: CISD2

Background:

Background: CDGSH iron sulfur domain 2 is a protein that in humans is encoded by the CISD2 gene. The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2.

Gene Full Name: CDGSH iron sulfur domain 2

Gene ID: 493856

UniProt: Q8N5K1

Pathways: Activation of Innate immune Response