CHMP2B antibody (AA 3-213) (HRP)

Catalog No. ABIN7978338

This Rabbit Polyclonal antibody specifically detects CHMP2B in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CHMP2B antibody (AA 3-213) (HRP) (ABIN7978338)

Target: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP2B antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CHMP2B Antibody (HRP)

Binding Specificity: AA 3-213

Purpose: Anti-CHMP2B Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CHMP2B recombinant protein (Position: S3-D213)

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHMP2B

Target: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Alternative Name: CHMP2B

Background:

Background: This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.

Gene Full Name: charged multivesicular body protein 2B

Gene ID: 25978

UniProt: Q9UQN3