CHMP2B antibody (AA 3-213) (PE)

Catalog No. ABIN7978340

The PE-conjugated Rabbit Polyclonal anti-CHMP2B antibody (ABIN7978340) specifically detects CHMP2B in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CHMP2B antibody (AA 3-213) (PE) (ABIN7978340)

Target: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP2B antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-CHMP2B Antibody (PE)

Binding Specificity: AA 3-213

Purpose: Anti-CHMP2B Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CHMP2B recombinant protein (Position: S3-D213)

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CHMP2B

Target: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Alternative Name: CHMP2B

Background:

Background: This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.

Gene Full Name: charged multivesicular body protein 2B

Gene ID: 25978

UniProt: Q9UQN3