DUOX2 antibody (AA 63-403) (Cy3)

Catalog No. ABIN7986421

The Rabbit Polyclonal anti-DUOX2 antibody is suitable to detect DUOX2 in samples from Rat and Mouse. It has been validated for FACS.

Quick Overview for DUOX2 antibody (AA 63-403) (Cy3) (ABIN7986421)

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUOX2 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-DUOX2 Antibody (Cy3)

Binding Specificity: AA 63-403

Purpose: Anti-Duox2 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Duox2 recombinant protein (Position: A63-D403).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DUOX2

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Alternative Name: Duox2

Background:

Background: Dual oxidase 2, also known as DUOX2 or ThOX2 (for thyroid oxidase), is an enzyme that in humans is encoded by the DUOX2 gene. The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.

Gene Full Name: dual oxidase 2

Gene ID: 214593

UniProt: B7ZWM4

Pathways: Thyroid Hormone Synthesis