GLIS3 antibody (AA 184-765) (APC)

Catalog No. ABIN7993363

The Rabbit Polyclonal anti-GLIS3 antibody is suitable to detect GLIS3 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for GLIS3 antibody (AA 184-765) (APC) (ABIN7993363)

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIS3 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-GLIS3 Antibody (APC)

Binding Specificity: AA 184-765

Purpose: Anti-GLIS3 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GLIS3 recombinant protein (Position: A184-P765).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GLIS3

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Alternative Name: GLIS3

Background:

Background: Zinc finger protein GLI3 is a protein that in humans is encoded by the GLI3 gene. This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.

Gene Full Name: GLIS family zinc finger 3

Gene ID: 169792

UniProt: Q8NEA6