Kallikrein 10 antibody (C-Term) (APC)

Catalog No. ABIN8003846

This Rabbit Polyclonal antibody specifically detects Kallikrein 10 in FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for Kallikrein 10 antibody (C-Term) (APC) (ABIN8003846)

Target: Kallikrein 10 (KLK10)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 10 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Kallikrein 10 Antibody (APC)

Binding Specificity: C-Term

Purpose: Anti-Kallikrein 10/KLK10 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 10.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Kallikrein 10

Target: Kallikrein 10 (KLK10)

Alternative Name: KLK10

Background:

Background: KLK10 (kallikrein-related peptidase 10) also known as kallikrein 10, PRSSL1 or NES1, belongs to the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers.KLK10 also contains 12 conserved cysteines in its protease domain that are expected to form 6 disulfide bonds, as in other serine proteases. RT-PCR detected variable levels of KLK10 expression in nearly all of the 35 adult and fetal tissues examined. The KLK10 gene contains 6 exons, the first of which is noncoding. By fluorescence in situ hybridization, Polikoff et al. (1997) mapped the PRSSL1 gene to 19q13.3. By genomic sequence analysis, Gan et al. (2000) mapped the KLK10 gene within the KLK gene cluster on chromosome 19q13. This cluster includes 13 KLK genes and 5 pseudogenes.

Gene Full Name: kallikrein related peptidase 10

Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

Gene ID: 5655

UniProt: O43240

Pathways: Complement System