Leptin antibody (AA 22-167) (APC)

Catalog No. ABIN8005375

The APC-conjugated Rabbit Polyclonal anti-Leptin antibody (ABIN8005375) specifically detects Leptin in FACS. The antibody is reactive with Rat samples.

Quick Overview for Leptin antibody (AA 22-167) (APC) (ABIN8005375)

Target: Leptin (LEP)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leptin antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Leptin Antibody (APC)

Binding Specificity: AA 22-167

Purpose: Anti-Leptin Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived rat Leptin recombinant protein (Position: V22-C167). Rat Leptin shares 83.6%,95.9% amino acid (aa) sequence identity with human,mouse Leptin,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived rat Leptin recombinant protein (Position: V22-C167). Rat Leptin shares 83.6% and 95.9% amino acid (aa) sequence identity with human and mouse Leptin, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Leptin

Target: Leptin (LEP)

Alternative Name: Lep

Background:

Background: Leptin have been found to be obese and diabetic and to have reduced activity, metabolism and body temperature. cDNA clones encoding Leptin have been isolated from human, simian, mouse, and rat cells. The expression of Leptin mRNA has been shown to be restricted to adipose tissue. Although regulation of fat stores is deemed to be the primary function of leptin, it also plays a role in other physiological processes, as evidenced by its multiple sites of synthesis other than fat cells, and the multiple cell types beside hypothalamic cells that have leptin receptors. Many of these additional functions are yet to be defined.

Gene Full Name: leptin

Gene ID: 25608

UniProt: P50596

Pathways: JAK-STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process