LNPEP antibody (AA 17-994)

Catalog No. ABIN8005842

The Rabbit Polyclonal anti-LNPEP antibody is suitable to detect LNPEP in samples from Human, Rat and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for LNPEP antibody (AA 17-994) (ABIN8005842)

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LNPEP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Grade: Carrier-free

Product Details anti-LNPEP Antibody

Binding Specificity: AA 17-994

Purpose: Anti-LNPEP Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-LNPEP Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LNPEP recombinant protein (Position: E17-T994).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LNPEP

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Alternative Name: LNPEP

Background:

Background: Leucyl/cystinyl aminopeptidase, also known as cystinyl aminopeptidase (CAP), insulin-regulated aminopeptidase (IRAP), human placental leucine aminopeptidase (PLAP), oxytocinase, and vasopressinase, is an enzyme of the aminopeptidase group that in humans is encoded by the LNPEP gene. This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: leucyl and cystinyl aminopeptidase

Molecular Weight: 117 kDa

Gene ID: 4012

UniProt: Q9UIQ6

Pathways: Regulation of long-term Neuronal Synaptic Plasticity