PER2 antibody (AA 751-850) (Biotin)

Catalog No. ABIN751260

Product Details anti-PER2 Antibody (Biotin)

Target: PER2 (Period Circadian Protein 2 (PER2))

Binding Specificity: AA 751-850

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PER2 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PER2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PER2

Target: PER2 (Period Circadian Protein 2 (PER2))

Alternative Name: PER2/Period circadian protein 2 (PER2 Products)

Synonyms: FASPS antibody, FASPS1 antibody, mKIAA0347 antibody, mPer2 antibody, rPER2 antibody, gPer2 antibody, fj43b09 antibody, wu:fj43b09 antibody, period circadian regulator 2 antibody, period circadian clock 2 antibody, PER2 antibody, Per2 antibody, per2 antibody

Background:

Synonyms: FASPS, FASPS1, Period circadian protein homolog 2, hPER2, Circadian clock protein PERIOD 2, PER2, KIAA0347

Background: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]

Gene ID: 8864

UniProt: O15055