MCU antibody (AA 51-351) (Cy3)

Catalog No. ABIN8010642

The Rabbit Polyclonal anti-MCU antibody is suitable to detect MCU in samples from Human, Mouse, Rat and Monkey. It has been validated for FACS.

Quick Overview for MCU antibody (AA 51-351) (Cy3) (ABIN8010642)

Target: MCU (Mitochondrial Calcium Uniporter (MCU))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCU antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-MCU Antibody (Cy3)

Binding Specificity: AA 51-351

Purpose: Anti-MCU Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MCU recombinant protein (Position: V51-D351).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MCU

Target: MCU (Mitochondrial Calcium Uniporter (MCU))

Alternative Name: MCU

Background:

Background: The mitochondrial calcium uniporter (MCU) is a transmembrane protein that allows the passage of calcium ions from a cell's cytosol into mitochondria. Its activity is regulated by MICU1 and MICU2, which together with the MCU make up the mitochondrial calcium uniporter complex. This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants.

Gene Full Name: mitochondrial calcium uniporter

Gene ID: 90550

UniProt: Q8NE86

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis