NDFIP2 antibody (AA 16-336) (Fluoro550)

Catalog No. ABIN8014144

The Fluoro550-conjugated Rabbit Polyclonal anti-NDFIP2 antibody (ABIN8014144) specifically detects NDFIP2 in FACS. The antibody is reactive with Human samples.

Quick Overview for NDFIP2 antibody (AA 16-336) (Fluoro550) (ABIN8014144)

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDFIP2 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-NDFIP2 Antibody (Fluoro550)

Binding Specificity: AA 16-336

Purpose: Anti-NDFIP2 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NDFIP2 recombinant protein (Position: M16-L336).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NDFIP2

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Alternative Name: NDFIP2

Background:

Background: NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene. The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

Gene Full Name: Nedd4 family interacting protein 2

Gene ID: 54602

UniProt: Q9NV92

Pathways: Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome