NDFIP2 antibody (AA 16-336)

Catalog No. ABIN8014162

The Mouse Monoclonal anti-NDFIP2 antibody (Clone 10D6D7) (ABIN8014162) specifically detects NDFIP2 in WB, FACS, IHC, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for NDFIP2 antibody (AA 16-336) (ABIN8014162)

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NDFIP2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Clone: 10D6D7

Product Details anti-NDFIP2 Antibody

Binding Specificity: AA 16-336

Purpose: Anti-NDFIP2 Antibody (monoclonal, 10D6D7)

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-NDFIP2 Antibody.(monoclonal, 10D6D7). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NDFIP2 recombinant protein (Position: M16-L336).

Isotype: IgG2b

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NDFIP2

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Alternative Name: NDFIP2

Background:

Background: NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene. The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

Gene Full Name: Nedd4 family interacting protein 2

Molecular Weight: 39 kDa

Gene ID: 54602

UniProt: Q9NV92

Pathways: Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome