NLRP7 antibody (AA 1-169) (HRP)

Catalog No. ABIN8015929

The HRP-conjugated Rabbit Polyclonal anti-NLRP7 antibody (ABIN8015929) specifically detects NLRP7 in ELISA, IHC and WB. The antibody is reactive with Human samples.

Quick Overview for NLRP7 antibody (AA 1-169) (HRP) (ABIN8015929)

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP7 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-NLRP7 Antibody (HRP)

Binding Specificity: AA 1-169

Purpose: Anti-NLRP7 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NLRP7 recombinant protein (Position: M1-L169).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NLRP7

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Alternative Name: NLRP7

Background:

Background: NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene. This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: NLR family pyrin domain containing 7

Gene ID: 199713

UniProt: Q8WX94

Pathways: Inflammasome