NUP214 antibody (AA 36-374) (Cy3)

Catalog No. ABIN8017300

The Cy3-conjugated Rabbit Polyclonal anti-NUP214 antibody (ABIN8017300) specifically detects NUP214 in FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for NUP214 antibody (AA 36-374) (Cy3) (ABIN8017300)

Target: NUP214 (Nucleoporin 214kDa (NUP214))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP214 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-NUP214 Antibody (Cy3)

Binding Specificity: AA 36-374

Purpose: Anti-NUP214 Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NUP214 recombinant protein (Position: K36-E374).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NUP214

Target: NUP214 (Nucleoporin 214kDa (NUP214))

Alternative Name: NUP214

Background:

Background: Nucleoporin 214 (Nup2014) is a protein that in humans is encoded by the NUP214 gene. The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t (6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Gene Full Name: nucleoporin 214

Gene ID: 8021

UniProt: P35658

Pathways: Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection