PDE3B antibody (C-Term) (APC)

Catalog No. ABIN8021418

The Rabbit Polyclonal anti-PDE3B antibody is suitable to detect PDE3B in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for PDE3B antibody (C-Term) (APC) (ABIN8021418)

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE3B antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-PDE3B Antibody (APC)

Binding Specificity: C-Term

Purpose: Anti-PDE3B Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PDE3B shares 96% amino acid (aa) sequence identity with both mouse,rat PDE3B.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PDE3B. Human PDE3B shares 96% amino acid (aa) sequence identity with both mouse and rat PDE3B.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PDE3B

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Alternative Name: PDE3B

Background:

Background: Enables 3',5'-cyclic-AMP phosphodiesterase activity. Involved in several processes, including negative regulation of angiogenesis, negative regulation of lipid catabolic process, and regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in membrane. Part of guanyl-nucleotide exchange factor complex.

Gene Full Name: phosphodiesterase 3B

Gene ID: 5140

UniProt: Q13370

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process