PGAP1 antibody (AA 166-904) (Biotin)

Catalog No. ABIN8024475

The Rabbit Polyclonal anti-PGAP1 antibody is suitable to detect PGAP1 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for PGAP1 antibody (AA 166-904) (Biotin) (ABIN8024475)

Target: PGAP1 (Post-GPI Attachment To Proteins 1 (PGAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGAP1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PGAP1 Antibody (Biotin)

Binding Specificity: AA 166-904

Purpose: Anti-PGAP1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PGAP1 shares 89%,88.5% amino acid (aa) sequence identity with mouse,rat PGAP1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PGAP1 recombinant protein (Position: K166-R904). Human PGAP1 shares 89% and 88.5% amino acid (aa) sequence identity with mouse and rat PGAP1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PGAP1

Target: PGAP1 (Post-GPI Attachment To Proteins 1 (PGAP1))

Alternative Name: PGAP1

Background:

Background: Post-GPI attachment to proteins 1 is a protein that in humans is encoded by the PGAP1 gene. The protein encoded by this gene functions early in the glycosylphosphatidylinositol (GPI) biosynthetic pathway, catalyzing the inositol deacylation of GPI. The encoded protein is required for the production of GPI that can attach to proteins, and this may be an important factor in the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi. Defects in this gene are a cause an autosomal recessive form of cognitive impairment.

Gene Full Name: post-GPI attachment to proteins inositol deacylase 1

Gene ID: 80055

UniProt: Q75T13

Pathways: Sensory Perception of Sound, Inositol Metabolic Process