RASAL3 antibody (AA 48-925) (Biotin)

Catalog No. ABIN8030749

The Biotin-conjugated Rabbit Polyclonal anti-RASAL3 antibody (ABIN8030749) specifically detects RASAL3 in WB, IHC and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for RASAL3 antibody (AA 48-925) (Biotin) (ABIN8030749)

Target: RASAL3 (RAS Protein Activator Like 3 (RASAL3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASAL3 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-RASAL3 Antibody (Biotin)

Binding Specificity: AA 48-925

Purpose: Anti-RASAL3 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human RASAL3 shares 82.4% amino acid (aa) sequence identity with mouse RASAL3.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RASAL3 recombinant protein (Position: R48-Q925). Human RASAL3 shares 82.4% amino acid (aa) sequence identity with mouse RASAL3.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RASAL3

Target: RASAL3 (RAS Protein Activator Like 3 (RASAL3))

Alternative Name: RASAL3

Background:

Background: This gene belongs to the Ras GTPase-activating proteins (RasGAP) family and encodes a protein with pleckstrin homology (PH), C2, and Ras GTPase-activation protein (RasGAP) domains. This protein is localized near or at the plasma membrane when expressed exogenously. Reduced expression of this gene in some cell lines resulted in increased levels of the active form of Ras (Ras-GTP), suggesting that this gene may play a role in negatively regulating the Ras signaling pathway. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: RAS protein activator like 3

Gene ID: 64926

UniProt: Q86YV0