TDGF1 antibody (AA 31-188) (Biotin)

Catalog No. ABIN8045828

This Rabbit Polyclonal antibody specifically detects TDGF1 in ELISA, WB and IHC. It exhibits reactivity toward Human.

Quick Overview for TDGF1 antibody (AA 31-188) (Biotin) (ABIN8045828)

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDGF1 antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TDGF1 Antibody (Biotin)

Binding Specificity: AA 31-188

Purpose: Anti-CRIPTO Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CRIPTO recombinant protein (Position: L31-Y188).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TDGF1

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Alternative Name: CRIPTO

Background:

Background: This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.

Gene Full Name: cripto, EGF-CFC family member

Gene ID: 6997

UniProt: P13385

Pathways: EGFR Signaling Pathway