TUB antibody (C-Term) (PE)

Catalog No. ABIN8050418

This Rabbit Polyclonal antibody specifically detects TUB in FACS. It exhibits reactivity toward Human.

Quick Overview for TUB antibody (C-Term) (PE) (ABIN8050418)

Target: TUB (Tubby Homolog (TUB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUB antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-TUB Antibody (PE)

Binding Specificity: C-Term

Purpose: Anti-TUB 1 Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse,rat sequences by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TUB 1, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TUB

Target: TUB (Tubby Homolog (TUB))

Alternative Name: TUB

Background:

Background: Tubby protein homolog is a protein that in humans is encoded by the TUB gene. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene Full Name: TUB bipartite transcription factor

Gene ID: 7275

UniProt: P50607

Pathways: RTK Signaling, Sensory Perception of Sound